PULMONARY ARTERIAL PRESSURE IN EXPERIMENTAL RENAL HYPERTENSION

Abstract

The pressure in the central pulmonary artery averages 28/11 and 28/9 mm. Hg. respectively in normotensive and hypertensive trained unanesthetized dogs. The range of pressures in the former is [image] mm. Hg. and in the latter it is [image] mm. Hg. A method is described for obtaining pulmonary pressures in trained unanesthetized dogs. Systemic hypertension caused by renal ischemia does not alter the pulmonary pressure. This was demonstrated when readings were made both in anesthetized dogs with chest open and in trained unanesthetized dogs. The humoral mediator appears to have a selective action on the systemic blood vessels and does not appear to act on the pulmonary vessels.