THE METABOLISM OF SPECIES OF STREPTOMYCES VI
Open Access
- 1 January 1953
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 65 (1), 37-44
- https://doi.org/10.1128/jb.65.1.37-44.1953
Abstract
Most of the known reactions of the tricarboxylic acid cycle are demonstrated in S. coelicolor with intact cells and extracts. Reactions shown include the incorporation of C14 from acetate[long dash]2[long dash]C14 into alpha-ketoglutarate, the oxidation of glucose, citrate, alpha-ketoglutarate, .succinate, fumarate, and malate, the decarboxylation of oxalacetate, the quantitative conversion of malate to pyruvate, the conversion of alpha-ketoglutarate to succinate, and the synthesis by cell-free extracts of citrate from pyruvate (or acetate) and malate. It is concluded that the cycle functions in this organism; no assessment of its quantitative importance is attempted.Keywords
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