A Comparative Study of the Effects of Glycerite of Hydrogen Peroxide and of Hexylresorcinol on the Bacteria of the Normal Mouth

Abstract

Glycerite of H2O2, derived from non-aqueous H2O2 (92%), or from urea peroxide (4%), in anhydrous glycerol containing Oxine (0.1%) as a secondary stabilizing agent was used as a mouth rinse in 10 expts. Comparisons were made between glycerite of H2O2 1:33 with S. T. 37, 1:2000, with water as an exptl. control. The initial count was followed by a 5 min. rinse and successive subsampling counts were taken at intervals of 10 min., and 1, 2, and 3 hrs. The normal mouth, with no meal, no water, and no mouth rinse, showed a gradual increase in bacterial population to 450% by 3 hrs. With a water rinse; the 3-hr. total was 336%. With S. T. 37, the 3-hr. total was 143%. With glycerite of H2O2, the 3-hr. count was 72%. The soln. is less irritating and causes a greater reduction in the number of oral organisms, both initially and over a longer period of time than the other solns. studied.