Abstract
A series of dogs were cross-circulated by means of polyethylene tubing connections between carotid artery and external jugular vein. The procedure effectively mixes the blood streams of the 2 animals and has a low mortality and morbidity. Mean blood pressure, pulse rate and temperature varied independently in the animals, and flows of from 200-700 cc/minute, are obtained. External regulation of flow in the cross-circulation technique is unnecessary for most investigative and therapeutic applications, as long as cannulae of the same size are used in both animals.