Oral Administration of Penicillin
- 29 May 1947
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 236 (22), 817-820
- https://doi.org/10.1056/nejm194705292362201
Abstract
THE role of penicillin administered by mouth has been reported on by several investigators,1 2 3 4 5 6 and the conclusion seems warranted that if the drug is given in sufficiently large doses, cures may be expected in susceptible infections. The optimal dose, as well as the necessity of preliminary or concurrent neutralization of the gastric acidity to avoid the inactivating influence of hydrochloric acid in the stomach when penicillin is administered orally, has been the subject of some controversy in the recent literature.2 3 4 , 7 To evaluate the latter point, penicillin blood levels were determined in a control group of over 600 subjects, plain calcium . . .Keywords
This publication has 9 references indexed in Scilit:
- The Absorption of Orally Administered PenicillinScience, 1946
- ADMINISTRATION OF PENICILLIN BY MOUTHJAMA, 1945
- PENICILLIN BY MOUTHJAMA, 1945
- THE TREATMENT OF PNEUMOCOCCIC PNEUMONIA WITH ORALLY ADMINISTERED PENICILLINJAMA, 1945
- ORAL PENICILLINJAMA, 1945
- Calcium Carbonate as an Antacid for Oral PenicillinScience, 1945
- Increasing and Prolonging Blood Penicillin Concentrations Following Intramuscular AdministrationScience, 1945
- ORAL ADMINISTRATION OF PENICILLINJAMA, 1945
- ADMINISTRATION OF PENICILLIN BY MOUTHJAMA, 1945