Synthesis and biological activity of human inhibin-like peptide-(1-31).
- 1 September 1984
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 81 (17), 5399-5402
- https://doi.org/10.1073/pnas.81.17.5399
Abstract
A peptide containing 31 amino acids with inhibin-like activity was synthesized by a solid-phase method. The synthetic product was shown to be homogeneous in high-performance liquid chromatography and paper electrophoresis. In the mouse pituitary incubation system, the follitropin-suppressing activity of the synthetic peptide was comparable to that of the natural product. It was also active in suppressing lutropin-releasing hormone-induced follitropin release in vivo in immature male rats.This publication has 12 references indexed in Scilit:
- Isolation, Structure, and Synthesis of a Human Seminal Plasma Peptide with Inhibin-Like ActivityScience, 1984
- Partial amino acid sequence of a human seminal plasma peptide with inhibin‐like activityFEBS Letters, 1984
- High-performance partition chromatography of peptides on a new cross-linked agaroseInternational Journal of Peptide and Protein Research, 1983
- Effect of porcine follicular fluid preparations on gonadotrophin secretion by the mouse pituitary gland in vitroJournal of Endocrinology, 1983
- ISOLATION AND CHARACTERIZATION OF INHIBIN FROM HUMAN SEMINAL PLASMA*Annals of the New York Academy of Sciences, 1982
- Effect of inhibin like factors on gonadotrophin release by the mouse pituitary in vitroActa Endocrinologica, 1981
- Inhibin — fact or artifactMolecular and Cellular Endocrinology, 1979
- HUMAN SOMATOTROPIN .55. SYNTHESIS AND GROWTH-PROMOTING ACTIVITY OF PEPTIDE ANALOGS OF CARBOXYL TERMINAL PLASMIN FRAGMENT1978
- Synthesis and analgesic activity of human .beta.-endorphinJournal of Medicinal Chemistry, 1977
- Dual Endocrine Activity of the TestesScience, 1932