A convenient approach to hydroxyethylene dipeptide isosteres as building blocks for enzyme inhibitors
- 1 March 1991
- journal article
- Published by Elsevier in Tetrahedron
- Vol. 47 (10-11), 1887-1894
- https://doi.org/10.1016/s0040-4020(01)96101-0
Abstract
No abstract availableThis publication has 21 references indexed in Scilit:
- Synthese enantiomerenreiner γ-Keto-δ-aminosäuren, zentrale Bausteine vieler EnzyminhibitorenEuropean Journal of Organic Chemistry, 1990
- N-(9-phenylfluoren-9-yl)-.alpha.-amino ketones and N-(9-phenylfluoren-9-yl)-.alpha.-amino aldehydes as chiral educts for the synthesis of optically pure 4-alkyl-3-hydroxy-2-amino acids. Synthesis of the C-9 amino acid MeBmt present in cyclosporinThe Journal of Organic Chemistry, 1990
- Transition structures for the aldol reactions of anionic, lithium, and boron enolatesThe Journal of Organic Chemistry, 1990
- Renin inhibitors based on dipeptide analogs. Incorporation of the hydroxyethylene isostere at the P2/P3 sitesJournal of Medicinal Chemistry, 1990
- Effective blocking of HIV‐1 proteinase activity by characteristic inhibitors of aspartic proteinasesFEBS Letters, 1989
- A New Synthesis of N-Protected α-Aminomethyl Ketones From GlycineSynthetic Communications, 1988
- .alpha.-Amino acids as chiral educts for asymmetric products. Alkylation of N-phenylfluorenyl .alpha.-amino ketones. Synthesis of optically pure .alpha.-alkyl carboxylic acidsJournal of the American Chemical Society, 1988
- Vom Screening zum Drug Design – Moderne Methoden der Wirkstoff-FindungPharmazie in unserer Zeit, 1988
- A short, stereoselective synthesis of the lactone precursor to 2R,4S,5S hydroxyethylene dipeptide isosteresThe Journal of Organic Chemistry, 1986
- CHIRALITY CONTROL BY KINETIC PROTONATION: ENANTIOSELECTIVE SYNTHESES OF (+)-VELBANAMINE, (−)-ISOVELBANAMINE, AND (+)-CLEAVAMINEChemistry Letters, 1982