Production of Fatty Liver in the Rat by Cortisone.

Abstract

Summary Cortisone acetate, 6.25 mg/day, consistently produces elevation in rat serum glycerides and cholesterol, and in hepatic lipid glycerides other than phospholipid. Hepatic phospholipid and cholesterol levels are not affected. The question whether this represents a primary effect on the liver or a secondary effect due to mobilization of peripheral fat is discussed.