Effects of dimethyl sulphoxide on the synthesis of plasma proteins in the human hepatoma HepG2. Induction of an acute-phase-like reaction
- 1 August 1988
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 253 (3), 927-930
- https://doi.org/10.1042/bj2530927
Abstract
Effects of dimethyl sulphoxide (Me2SO) on the synthesis of plasma proteins by the human hepatoma cell line HepG2 were examined. Me2SO treatment resulted in decreased synthesis of albumin and alpha-fetoprotein, and in increased synthesis of haptoglobin. Plasma-protein profiles induced by Me2SO treatment were very similar to those seen in acute-phase reactions.This publication has 33 references indexed in Scilit:
- A Rauscher‐virus‐induced T‐lymphocyte cell line. Induction of differentiation under influence of dimethylsulfoxide and phorbolestersInternational Journal of Cancer, 1983
- Synthesis and regulation of acute phase plasma proteins in primary cultures of mouse hepatocytes.The Journal of cell biology, 1983
- INDUCTION OF DIFFERENTIATION IN HERPETOMONAS-SAMUELPESSOAI BY DIMETHYLSULFOXIDE1981
- Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell lineNature, 1979
- APPLICATION OF ELECTRO-IMMUNOASSAY TO THE STUDY OF PLASMA-PROTEIN SYNTHESIS IN CULTURED HEPATOCYTES1979
- Erythroleukemic DifferentiationAnnual Review of Biochemistry, 1978
- Cytochrome P-450 heme and the regulation of hepatic heme oxygenase activityArchives of Biochemistry and Biophysics, 1976
- Dimethylsulfoxide-induced differentiation and hemoglobin synthesis in tissue cultures of rat erythroleukemia cells transformed by 7,12-dimethylbenz(a)anthracene.Proceedings of the National Academy of Sciences, 1976
- Maturation of neuroblastoma cells in the presence of dimethylsulfoxide.Proceedings of the National Academy of Sciences, 1976
- Variation with age and disease of an amyloid A protein-related serum component.Journal of Clinical Investigation, 1975