Investigations on the polymorphism of glyoxalase I (EC 4.4.1.5) in the population of Hessen, Germany
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 38 (1), 99-106
- https://doi.org/10.1007/bf00295812
Abstract
The phenotypes of glyoxalase I (GLO) were determined in a random population from Hessen (Germany) by high-voltage agarose gel electrophoresis. The gene frequencies in 1150 unrelated individuals were 0.4391 for GLO1 and 0.5609 for GLO2. Rare phenotypes were not observed. The segregation of phenotypes in 50 families and 32 mother-child combinations supports the assumed autosomal codominant inheritance. The possibility of a simultaneous typing for GLO, esterase D (EsD), and carbonic anhydrase2 (CA2) on one gel is discussed.Keywords
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