Effects of Various Anesthetic Agents on the Blood Pressure of the White Rat.

Abstract

A simplified modification of the tail plethysmograph method of Byrom and Wilson using the pressure cuff described by Griffith and Jeffers was used. The mean arterial systolic pressure in the unanesthetized animal was 124.8 mm. Hg. The mean pressures obtained* by the use of anesthetic agents were as follows: nembutal-104.1, amytal- 103.5, ether (shallow)- 117, ether (deep) 104, urethane- 78.4, morphine- 63.9 mm. Hg.