Enlarged Gastric Rugae: A Correlation of the Roentgenologic, Gastroscopic, Pathologic, and Clinical Findings

Abstract

41 cases of marked chronic enlargement of the mucosal folds during roentgenologic examination were analyzed. Chronic and recurring indigestion which was usually aggravated by food was present in 27 patients, while the reMalning 14 had ulcer-like symptoms. Fractional gastric analysis, with histamine as a stimulant, showed an absence of free HC1 in 12 cases. Pathologic studies were done on 8, and all showed a chronic gastritis. The roentgen findings were characterized by chronic enlargement of the mucosal folds and irregular and sluggish peristalsis, with limited motility of the gastric mucosa.