Studies on Production of Antipoliomyelitis Serum in Rabbits.

Abstract
Type specific neutralizing antibodies were produced in rabbits inoculated with the 3 types of poliomyelitis virus grown in tissue culture. Rabbits were successfully immunized by repeated intravenous or intramuscular inoculations of active or UV irradiated virus suspensions. The possibilities of a rabbit test for assay of poliomyelitis vaccine are discussed.