Treatment of Kaposi's Sarcoma of the Lower Extremity by Extracorporeal Perfusion with Chemotherapeutic Agents

Abstract

KAPOSI'S sarcoma, or "idiopathic multiple hemorrhagic sarcoma," was first described as a clinical entity by Kaposi in 1872. The disease is progressive, and it exhibits a wide range of clinical and histologic variations. It has a singular propensity for the male Jewish and Italian population of Eastern Europe, is common in the African Negro, but rarely affects the female.^{1 2 3 4} Although the disease is reported in adolescence,¹ its onset is usually in persons over forty, with a progressively increasing incidence in succeeding decades.The initial lesion is most often found on the hands and feet, and it takes the form of . . .