Tyrosinase-cytalyzed conjugation of dopa with glutathione
- 1 July 1985
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 41 (7), 960-961
- https://doi.org/10.1007/bf01970033
Abstract
Summary A convenient method is described for the preparation of 5-S- and 2-S-glutathionyldopa, based on tyrosinase oxidation of dopa in the presence of glutathione. The yields of 5-S, 2-S, and 6-S isomers produced were about 76, 12, and 5%, respectively.Keywords
This publication has 10 references indexed in Scilit:
- Cysteinyldopa isomers and dopa in lesions and urine of Japanese patients with malignant melanomaArchives of Dermatological Research, 1983
- Characterization of Structural Properties for Morphologic Differentiation of Melanosomes. III. Free and Protein-bound Dopa and 5-S-Cysteinyldopa in B16 and Harding-Passey MelanomasJournal of Investigative Dermatology, 1983
- Role of Thiol Compounds in Mammalian Melanin Pigmentation. II. Glutathione and Related Enzymatic ActivitiesJournal of Investigative Dermatology, 1982
- Urinary free and conjugated 5-S-cysteinyldopa in normal subjects and in patients with melanomaBritish Journal of Dermatology, 1982
- Formation of glutathionedopa in albino rats after DOPA injectionActa Dermato-Venereologica, 1981
- Synthesis and antitumor activity of cysteinyl-3,4-dihydroxyphenylalonines and related compoundsJournal of Medicinal Chemistry, 1981
- The effect of cysteine on oxidation of tyrosine dopa, and cysteinyldopasArchives of Dermatological Research, 1981
- Distribution and metabolism of tritium-labelled 5-5-cysteinyldopa in miceBiochemical Pharmacology, 1980
- A facile one-step synthesis of cysteinyldopas using mushroom tyrosinaseCellular and Molecular Life Sciences, 1977
- Glutathionedopa in malignant melanomaActa Dermato-Venereologica, 1977