Carcinoma of the Lung with Inappropriate Antidiuresis

Publisher Website
Google Scholar
Abstract
THE association of carcinoma of the lung with hyponatremiaand renal sodium loss has been reported on several occasions. Schwartz et al.1 first demonstrated the presence of inappropriate antidiuresis in patients with this syndrome and suggested that it was due to inappropriate secretion of antidiuretic hormone. There have been no reports of elevated levels of vasopressin in the blood of such patients. Even in maximal antidiuresis, however, peripheral blood concentrations of vasopressin could easily escape detection by presently available methods for extraction and biologic assay. The pathogenesis of the syndrome has been obscure, but a neurogenic basis due to involvement of . . .