Effect of Atropine and Methiamide on Vagally Induced Gastric Acid Secretion and Gastrin Release in Anesthetized Cats
- 1 April 1977
- journal article
- research article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 99 (4), 496-502
- https://doi.org/10.1111/j.1748-1716.1977.tb10403.x
Abstract
Gastrin release and HCl secretion was induced by electrical vagal stimulation in anesthetized cats. Both atropine (0.1-0.3 mg/kg) and methiamide (4-20 mg/kg) inhibited the HCl secretion (by .apprx. 60 and .apprx. 80%). Neither atropine (0.2-2 mg/kg) nor methiamide (20 mg/kg) inhibited the vagally induced gastrin release. Possible explanations of the atropine resistance of the vagal gastrin release mechanism are discussed.This publication has 15 references indexed in Scilit:
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