Synthèse d'homologues de la lysine‐vasopressine et de l'oxytocine contenant une séquence His‐Sér ou Sér‐His en position N‐terminale
- 1 January 1962
- journal article
- research article
- Published by Wiley in Helvetica Chimica Acta
- Vol. 45 (7), 2517-2528
- https://doi.org/10.1002/hlca.19620450722
Abstract
(His‐Ser‐Cys)1‐lysine‐vasopressin, (Ser‐His‐Cys)1‐lysine‐vasopressin, (His‐Ser‐Cys)1‐oxytocin and (Ser‐His‐Cys)1‐oxytocin have been synthesized by condensing dipeptide azides with nonapeptides. The first peptide was also prepared by reacting a pentapeptide azide with an hexapeptide. It exhibits a noteworthy ACTH‐releasing activity in vivo and a better specificity than lysine‐vasopressin.This publication has 19 references indexed in Scilit:
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