Highly Efficient CuBr‐Catalyzed Cross‐Dehydrogenative Coupling (CDC) between Tetrahydroisoquinolines and Activated Methylene Compounds
- 14 July 2005
- journal article
- research article
- Published by Wiley in European Journal of Organic Chemistry
- Vol. 2005 (15), 3173-3176
- https://doi.org/10.1002/ejoc.200500226
Abstract
A novel and efficient C–C bond‐formation method was developed: the cross‐dehydrogenative coupling (CDC) reaction catalyzed by copper bromide in the presence of an oxidizing reagent, tBuOOH. The CDC reaction provides a simple and efficient catalytic method to construct β‐amino diesters and β‐dicyano amines by a combination of two different sp3 C–H bonds followed by C–C bond formation. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)This publication has 23 references indexed in Scilit:
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