Effects of Thermal Injury and of Skin Removal on Thyroid Function in the Rat

Abstract
Thyroid I131 release rates have been measured in 6 rats before and after a 10–20% full thickness burn of the skin, and in 11 rats before and after resection of 10–20% of the dorsal skin surface. Thyroid function was inhibited for a variable period up to 30 hours after the burn in five of six animals. In contrast, flaying was followed in each of the 11 rats by increased thyroid function.