CONVERSION OF GENETIC RESISTANCE OF MAMMALIAN CELLS TO SUSCEPTIBILITY TO A VIRUS INFECTION
- 1 September 1962
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 48 (9), 1553-1559
- https://doi.org/10.1073/pnas.48.9.1553
Abstract
Macro-phages obtained from peritoneal washings of mice which are genetically resistant to mouse hepatitis are resistant to this virus in culture. Similar cells from susceptible mice are susceptible in culture. Susceptibility can be confirmed on the resistant cells by treatment of these cells with a heat-stable factor extracted from the susceptible cells. This factor must be given in sufficient concentration to produce the conversion to susceptibility. The nature of the factor is under investigation.Keywords
This publication has 4 references indexed in Scilit:
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- MOUSE MACROPHAGES AS HOST CELLS FOR THE MOUSE HEPATITIS VIRUS AND THE GENETIC BASIS OF THEIR SUSCEPTIBILITYProceedings of the National Academy of Sciences, 1960
- Macrophages and mouse hepatitisVirology, 1959
- [Artificial peritoneal exudate, source of cells for virus culture in vitro].1955