Radioimmunolocalization of Tumours by External Scintigraphy after Administration of131I Antibody to Human Chorionic Gonadotrophin: Preliminary Communication
- 1 September 1980
- journal article
- Published by SAGE Publications in Journal of the Royal Society of Medicine
- Vol. 73 (9), 624-630
- https://doi.org/10.1177/014107688007300905
Abstract
(131)Iodine ((131)I) labelled antibody directed against human chorionic gonadatrophin (hCG) was given on 21 occasions to 18 patients with hCG-producing neoplasms. Tumours were localized by external scintigraphy in 13 of 21 investigations. Positive results were obtained reliably when serum hCG exceeded 500 miu/ml and in some cases sensitivity was comparable to that of computerized tomography. A positive result probably implies viability in the tumour and this was of practical value in discriminating between necrotic deposits and living tumour before surgery.Keywords
This publication has 10 references indexed in Scilit:
- Tumor Localization of Radio-Labeled Antibodies against Carcinoembryonic Antigen in Patients with CarcinomaNew England Journal of Medicine, 1980
- RADIOIMMUNOLOCALISATION OF TUMOURS BY EXTERNAL SCINTIGRAPHY AFTER ADMINISTRATION OF 131I ANTIBODY TO CARCINOEMBRYONIC ANTIGENNuclear Medicine Communications, 1980
- Localisation of tumour deposits by external scanning after injection of radiolabelled anti-carcinoembryonic antigen.BMJ, 1980
- Chemotherapy of Advanced Malignant TeratomasPublished by Springer Nature ,1980
- Use of Radiolabeled Antibodies to Carcinoembryonic Antigen for the Detection and Localization of Diverse Cancers by External PhotoscanningNew England Journal of Medicine, 1978
- LOCALIZATION OF GW-39 HUMAN TUMORS IN HAMSTERS BY AFFINITY-PURIFIED ANTIBODY TO CARCINOEMBRYONIC ANTIGEN1977
- A rapid, sensitive and specific radioimmunoassay for human chorionic gonadotrophinJournal of Immunological Methods, 1976
- In vivo localisation of radiolabelled antibodies to carcinoembryonic antigen in human colon carcinoma grafted into nude miceNature, 1974
- Studies on Antigen-Antibody ComplexesThe Journal of Immunology, 1971
- A Method of Trace Iodination of Proteins for Immunologic StudiesInternational Archives of Allergy and Immunology, 1966