CORTICOSTERONE AND ITS ESTERS

Abstract
Pure samples of the acetate, propionate, butyrate, succinate, caproate, diethyl acetate, heptoate, palmitate and benzoate of corticosterone were prepared and assayed by subcut. inj. in adrenalectomized rats. The diethyl acetate was found most active, being 4 times as active as free corticosterone. Of the straight chain esters, the butyrate was found most active. Corticosterone Na succinate in aq. soln. was found less active than free corticosterone in oil soln.