A NEW SUBSTANCE WITH PROGESTATIONAL ACTIVITY
- 1 August 1956
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 22 (4), 303-317
- https://doi.org/10.1530/acta.0.0220303
Abstract
Sublingual administration of 17-methyl-19-nortestosterone (I) produced a progestational type of endometrium in women on a single daily sublingual standard dose of 50 [mu]g of ethinyl estradiol. I was 150 times as active as progesterone (n) and at least 50 times as active as 17[alpha]-ethinyl testosterone given by the same route. I given by the sublingual route was about 10 times as active as II given by injection. Thera-peutically I was found to be effective in sublingual doses of 1 to 12.5 mg/24 hours.This publication has 9 references indexed in Scilit:
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