Das Schicksal peroral verabreichten Cholesterins und Koprosterins im menschlichen Darm.

Abstract

Cholesterol administered by mouth to a patient with a carcinoma of the bile ducts, bile secretion into the duodenum being impossible, was practically quantitatively absorbed provided that sufficient solvent was present. Koprosterol administered in the same way was found almost quantitatively in the feces; the same is true of synthetic dihydrocholesterol. The absorption of the sterols in the human digestive tract depends not only on physical chemical factors but also, as is shown here, on the chemical constitution of the molecule. Koprosterol can be considered as the physiological end-product of the sterol cycle.