Breast Milk Jaundice: Effect of Inhibitory Breast Milk and 3 ,20 - Pregnanediol on Glucuronyl Transferase
Open Access
- 1 April 1971
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 46 (246), 195-198
- https://doi.org/10.1136/adc.46.246.195
Abstract
The effect of breast milk and 3α, 20β-pregnanediol on the conjugation of bilirubin and o-aminophenol by rat liver was compared. Breast milk inhibited glucuronyl transferase, whereas 3α, 20β-pregnanediol inhibited the secretion of bilirubin glucuronide from rat liver slices. In the inhibitory breast milk examined the steroid was probably not the sole inhibitory factor.Keywords
This publication has 12 references indexed in Scilit:
- Breast Milk Jaundice: Effect of 3 20 -pregnanediol on Bilirubin Conjugation by Human LiverArchives of Disease in Childhood, 1970
- Determination of bilirubin glucuronide and assay of glucuronyltransferase with bilirubin as acceptorBiochemical Journal, 1968
- The effect of pregnanediol and pregnanediol glucuronide on bilirubin conjugation by rat liver slices.1965
- The estimation of bilirubin in liverClinica Chimica Acta; International Journal of Clinical Chemistry, 1965
- Production of Unconjugated Hyperbilirubinæmia in Full-term New-born Infants following Administration of Pregnane-3(alpha), 20(beta)-diolNature, 1964
- HEPATIC TRANSPORT OF BILIRUBINAnnals of the New York Academy of Sciences, 1963
- Glucuronide synthesis in kidney and gastrointestinal tractBiochemical Journal, 1962
- The synthesis of bilirubin glucuronide in animal and human liverBiochemical Journal, 1958
- INHIBITION OF BILIRUBIN CONJUGATION IN RAT LIVER SLICES BY HUMAN PREGNANCY AND NEONATAL SERUM AND STEROIDSQuarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1958
- Hepatic clearance of bilirubin as an index of cellular function in the regenerating rat liver.1956