Radioprotection by WR-2721 against Long-Term Chronic Damage to the Rat Parotid Gland
- 1 October 1978
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 76 (1), 172-179
- https://doi.org/10.2307/3574936
Abstract
WR-2721 [S-2-(3-aminopropylamino)ethylphosphorothioic acid] protected against the acute phase of radiation damage which is manifest during the 1st wk after irradiation, though recovery occurred both in the presence and absence of such protection. The drug also protected against the chronic phase damage which appeared later (60-90 days postirradiation), with dose modification factors of 2.3 for gland weight, 3.2 for amylase and 2.0 for total gland amylase and R increases ranging from 1.7-4.9 kR.This publication has 4 references indexed in Scilit:
- Short-Term Radioprotective Effects of WR-2721 on the Rat Parotid GlandsRadiation Research, 1978
- Effects of X-irradiation and the resultant inanition on amylase content of the rat parotid glandArchives of Oral Biology, 1977
- Protection of normal tissues by WR2721 during fractionated irradiationInternational Journal of Radiation Oncology*Biology*Physics, 1976
- Chemoprotection against Fractionated Radiation Exposures with WR-2721: Skin InjuryRadiation Research, 1976