Prophylactic use of cephazolin against wound sepsis after cholecystectomy.
- 14 May 1977
- Vol. 1 (6071), 1254-1256
- https://doi.org/10.1136/bmj.1.6071.1254
Abstract
A trial of antibiotic prophylaxis with cephazolin against postoperative wound sepsis was carried out on 201 patients undergoing routine cholecystectomy. Wound sepsis occurred in 11 out of 65 controls (16.9%), who were not given the drug; two out of 63 patients (3.2%) given a single dose preoperatively; and four out of 73 patients (5.5%) given the single preoperative dose plus a five-day course postoperatively. The difference between the controls and patients given the single preoperative dose was significant.Keywords
This publication has 19 references indexed in Scilit:
- Prophylactic lincomycin in the prevention of wound infection following appendicectomy: A double blind studyBritish Journal of Surgery, 1976
- Antibiotic Prophylaxis in Gastric, Biliary and Colonic SurgeryAnnals of Surgery, 1976
- CHANGING PATTERNS OF BACTERIAL RESISTANCE IN RELATION TO PROPHYLACTIC USE OF CEPHALORIDINE AND THERAPEUTIC USE OF AMPICILLINThe Lancet, 1975
- A controlled trial of parenteral prophylactic gentamicin therapy in biliary surgeryBritish Journal of Surgery, 1975
- Short term routine antibiotic prophylaxis in surgeryBritish Journal of Surgery, 1974
- The reduction of surgical wound infections by prophylactic parenteral cephaloridine: A controlled clinical trialBritish Journal of Surgery, 1973
- The effect of a single-dose parenteral antibiotic in the prevention of wound infection a controlled trialBritish Journal of Surgery, 1972
- Clinical studies of cefazolin in the surgical field.1970
- AMPICILLIN LEVELS IN HUMAN BILEBritish Journal of Pharmacology and Chemotherapy, 1965
- Bacteriological investigation of the biliary system and liver in biliary tract disease correlated to clinical data and microstructure of the gallbladder and liver.1959