Plaque Acid Production in Hamsters Pretreated with Fluoride

Abstract
Plaque acid production in hamsters pretreated with fluoride did not differ from that in untreated control hamsters, although sufficient fluoride was present in the teeth of the treated hamsters to protect against a severe cariogenic challenge. The results indicate that enamel-bound fluoride does not significantly influence carbohydrate metabolism of microbial plaques.