Luteinization of the Ovaries of Immature Hypophysectomized Parabiotic Rats with Gonadotrophic Hormone Preparations.

Abstract

The injn. of LH, gonadotrophin prepared from the urine, of pregnant women, and unfractionated sheep pituitary extracts into the non-hypophyseetomized partner produced luteinization in the ovaries of the hypophysectomized partner of either hypophysectomized-gonadectomized or hypophysectomized-normal parabiotic rats. The results indicate that the failure of the ovaries of the hypophysectomized partner of hypophysec-tomized-gonadectomized pairs to develop corpora lutea is due to an insufficient secretion of LH following gonadectomy rather than to an unresponsive state of the ovaries of the hypophysectomized animal.