Gonadotrophic Hormone Secretion in Immature Hypophysectomized Parabiotic Rats.

Abstract

Using immature hypophysectomized-gonadectomized parabiotic rats, it has been demonstrated that following gonad removal in both sexes follicular stimulation only is obtained in the ovaries of the hypophysectomized parabiont for as long as 53 days following the operation. If the hypophysectomized partner is a [male], the testes are maintained in the scrotum and their avg. wt. is somewhat less than that of normals, whereas the weight of the accessory glands is approx. the same as that of normal animals. Approx. 17% of the pairs failed to show any gonadal stimulation following the hypophysectomy-goiiadectomy procedure. This percentage failure is slightly greater than that occurring in non-hypophysectomized pairs.