Relation of Secondary Antigen Injection to Time of Irradiation on Antibody Production in Mice
- 31 July 1959
- journal article
- research article
- Published by The American Association of Immunologists in The Journal of Immunology
- Vol. 83 (2), 184-188
- https://doi.org/10.4049/jimmunol.83.2.184
Abstract
The maximum depression period of the secondary antibody response takes place when antigen is injected 1 day before to 1 hr after x-radiation. Recovery of the secondary immune mechanism of irradiated mice takes place within 2 weeks. Above-normal mean total titers were observed when a second antigen injection is given 5 and 10 days after 710 r. No significant decrease or increase in mean peak titer was observed regardless of the x-radiation-secondary antigen injection time relationship.Keywords
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