Loss of Cytotoxicity of Rabbit Anti-Ehrlich Ascites Tumor Cell Antibody Following Pepsin Digestion
- 1 September 1966
- journal article
- research article
- Published by The American Association of Immunologists in The Journal of Immunology
- Vol. 97 (3), 386-392
- https://doi.org/10.4049/jimmunol.97.3.386
Abstract
Pepsin digestion of cytotoxic 6.6S rabbit Ehrlich ascites tumor cell antibody produces 4.8S antibody which has lost its ability to bind hemolytic guinea pig complement and is not cytotoxic.This publication has 12 references indexed in Scilit:
- PEPSIN DIGESTION OF RABBIT AND SHEEP ANTIBODIESThe Journal of Experimental Medicine, 1963
- Antibody to Rat Kidney: In vivo Effects of Univalent and Divalent FragmentsScience, 1963
- Passive Cutaneous Anaphylaxis with Antibody FragmentsScience, 1963
- The Nature of Antibodies and AntigensAnnual Review of Microbiology, 1962
- Complement Fixation by Antibody FragmentsScience, 1961
- Interaction of Fragment III of Rabbit Gamma Globulin and Guinea Pig Complement.Experimental Biology and Medicine, 1961
- Separation of univalent fragments from the bivalent rabbit antibody molecule by reduction of disulfide bondsArchives of Biochemistry and Biophysics, 1960
- The hydrolysis of rabbit γ-globulin and antibodies with crystalline papainBiochemical Journal, 1959
- The relative transmission of natural and pepsin-refined homologous antitoxin from the uterine cavity to the foetal circulation in the rabbitProceedings of the Royal Society of London. B. Biological Sciences, 1959
- Enzymatic Digestion of Rabbit Globulin.Experimental Biology and Medicine, 1959