Absorption of Di‐ and triglycerides by intestinal slices in vitro

Abstract

The uptake by hamster intestinal rings of labeled 1,3-diolein and triolein in bile salt emulsions was studied. About 6% of triolein was taken up from emulsions containing glycerides and fatty acid in 6 mM sodium taurodeoxycholate. Lesser uptake was noted when triolein was emulsified with lecithin, cholesterol and bile salt; lowest uptake (3%) was observed from triolein-lecithincholesterol emulsions prepared without bile salt. Absorption of 1,3-diolein from bile salt emulsion was greater and acylation to triglyceride was observed. Diglycerides and triglycerides in small quantity may be absorbed intact from a micellar phase.