Abstract
Hypophysectomized rats receiving FSH immediately following operation showed no interruption of sperm formation within 40 days of treatment; accessory structures underwent early regression showing that the secretion of the S hormone had not been prolonged. When treatment was delayed 15 days the atrophic tubules were restored to full spermatogenesis. Injs. of LH sustained both the gametogenic and endocrine activity for a time. Partial regression of accessories occurred after 30 or 40 days of treatment, but spermatogenesis was not impaired. LH given after 15 days of atrophy induced interstitial cell repair and resumption of spermatogenesis.