HORDENINE AS THE PRECURSOR OF NDMA IN MALT
Open Access
- 8 July 1981
- journal article
- research article
- Published by The Institute of Brewing & Distilling in Journal of the Institute of Brewing
- Vol. 87 (4), 259-263
- https://doi.org/10.1002/j.2050-0416.1981.tb04028.x
Abstract
Hordenine can be nitrosated by gaseous oxides of nitrogen (NOx) or by nitrite at acidic pH to form N-nitrosodimethylamine (NDMA). Descending paper chromatography of an amine fraction from malt shows that a precursor of NDMA co-chromatographs with hordenine. Measurements of hordenine in malt show that it is present at levels greatly exceeding those needed to form high levels of NDMA. A rapid method for the measurement of hordenine in malt using High Performance Liquid Chromatography (HPLC) is described.Keywords
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