A COMPARISON OF THE BLOOD PRESSURE, KIDNEY VOLUME AND THE PANCREATIC SECRETORY RESPONSE FOLLOWING THE VEIN ADMINISTRATION OF VARIOUS SECRETIN PREPARATIONS

Abstract

The administration of secretins by vein or dilute HCl by intestine accelerates the external pancreatic secretory flow by 2 supplementary actions, i.e., increased splanchnic blood flow and direct stimulation of the secretory mechanism. The order of the secretagogue efficiency of the preparations tested, from the greatest to the least, was HCl in the intestine, and the following secretins: Bayliss and Starling, "new'' vasodilatin free, purified Bayliss and Starling, Dale and Laidlaw.