Abstract
The relation between total energy intake and the development of ischaemic heart disease was investigated from a review of all available data including the results of 26 years of follow up from a longitudinal study of diet and ischaemic heart disease. A consistent inverse relation was found, whose strength and consistency are similar to those of other established risk factors. It is concluded that there may be a minimum energy intake below which the risk of ischaemic heart disease is increased.