A Novel Method for Large-Scale Synthesis of Lamivudine through Cocrystal Formation of Racemic Lamivudine with (S)-(−)-1,1′-Bi(2-naphthol) [(S)-(BINOL)]
- 21 January 2009
- journal article
- Published by American Chemical Society (ACS) in Organic Process Research & Development
- Vol. 13 (3), 450-455
- https://doi.org/10.1021/op800228h
Abstract
No abstract availableThis publication has 26 references indexed in Scilit:
- BINOL: A Versatile Chiral ReagentChemical Reviews, 2005
- New Enantioselective Routes to Cyclic and Acyclic S,O-acetals; Enzymatic Resolution of α-Acetoxy Sulfides and Enantioselective Synthesis of the Antiviral Agent LamivudinePhosphorus, Sulfur, and Silicon and the Related Elements, 1997
- ‘Polymorphism’ in a novel anti-viral agent: LamivudineJournal of the Chemical Society, Perkin Transactions 2, 1997
- Solubility Behavior of Lamivudine Crystal Forms in Recrystallization SolventsJournal of Pharmaceutical Sciences, 1996
- Diastereoselective Synthesis of the Potent Antiviral Agent (-)-2'-Deoxy-3'-thiacytidine and Its EnantiomerThe Journal of Organic Chemistry, 1995
- The Resolution and Absolute Stereochemistry of the Enantiomers ofcis-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine (BCH189): Equipotent Anti-HIV AgentsNucleosides and Nucleotides, 1993
- Enzyme-mediated enantioselective preparation of pure enantiomers of the antiviral agent 2',3'-dideoxy-5-fluoro-3'-thiacytidine (FTC) and related compoundsThe Journal of Organic Chemistry, 1992
- Synthesis of Tetrazole Oxathiolane Nucleoside Analogues and Their Evaluation as HIV-1 Antiviral AgentsNucleosides and Nucleotides, 1992
- Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)The Journal of Organic Chemistry, 1992
- An efficient synthesis of enantiomerically pure (+)-(2S,5R)-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine [(+)-BCH-189] from d-galactoseTetrahedron Letters, 1992