RESPONSE OF NORMAL SUBJECTS TO ACUTE BLOOD LOSS
- 1 September 1941
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Internal Medicine
- Vol. 68 (3), 578-590
- https://doi.org/10.1001/archinte.1941.00200090205009
Abstract
Studies on the response of the body to acute blood loss are of both theoretic and practical importance because hemorrhage is a serious complication in many medical and surgical conditions. In man, controlled observations on the effect of hemorrhage on the circulation, the plasma volume, the protein concentration and the cell-plasma ratio are difficult to obtain because the immediate care of the patient requires the complete attention of the physician and because the amount of blood lost is not known. In addition, the underlying disease producing the hemorrhage may alter the response of the body. Although many investigators have studied the effect of acute blood loss on lower animals, few studies on human subjects have been made under controlled conditions. Keith1 observed changes in hematocrit reading and blood volume as determined by the dye method after the removal of 800 cc. of blood from a normal man. He foundThis publication has 11 references indexed in Scilit:
- THE EFFECT OF THE APPLICATION OF TOURNIQUETS ON THE HEMODYNAMICS OF THE CIRCULATIONJCI Insight, 1940
- PLASMA PROTEINS: THEIR SOURCE, PRODUCTION AND UTILIZATIONPhysiological Reviews, 1940
- ELECTROPHORETIC ANALYSIS OF PLASMA AND URINARY PROTEINSJCI Insight, 1940
- CLINICAL STUDIES OF THE BLOOD VOLUME. VII. CHANGES IN BLOOD VOLUME IN BRIGHT'S DISEASE WITH OR WITHOUT EDEMA, RENAL INSUFFICIENCY, OR CONGESTIVE HEART FAILURE, AND IN HYPERTENSION 1JCI Insight, 1939
- A SIMPLE METHOD FOR THE ESTIMATION OF TOTAL PROTEIN CONTENT OF PLASMA AND SERUM. II. THE ESTIMATION OF TOTAL PROTEIN CONTENT OF HUMAN PLASMA AND SERUM BY THE USE OF THE FALLING DROP METHODJCI Insight, 1938
- CLINICAL STUDIES OF THE BLOOD VOLUME. IV. ADAPTATION OF THE METHOD TO THE PHOTOELECTRIC MICROCOLORIMETERJCI Insight, 1938
- CLINICAL STUDIES OF THE BLOOD VOLUME. I. CLINICAL APPLICATION OF A METHOD EMPLOYING THE AZO DYE “EVANS BLUE” AND THE SPECTROPHOTOMETERJCI Insight, 1937
- THE NATURE OF CIRCULATORY COLLAPSE INDUCED BY SODIUM NITRITE 1JCI Insight, 1937
- THE RATE OF ENTRANCE OF FLUID INTO THE BLOOD IN HEMORRHAGEAmerican Journal of Physiology-Legacy Content, 1933
- The effects of posture on the circulating blood volumeThe Journal of Physiology, 1931