INVAGINATIONS DE LA MEMBRANE NUCLÉAIRE DANS LA CELLULE DE PURKINJE CHEZ LE RAT ADULTE

Abstract

On the basis of a light-microscope study, evidence is presented that nuclear membrane invaginations are of normal and regular occurrence in the Purkinje cell of the cerebellar cortex in the adult rat. In cerebella fixed by perfusion with Helly fixative, osmic acid, or glutaraldehyde followed by osmic acid, these invaginations, which vary in size, shape, and topographical distribution, are usually seen to emerge from the ectal nuclear cap and are often observed to extend to the vicinity of the nucleolus or the paranucleolar masses. Such invaginations contain a material which exhibits the cytochemical characteristics of the ribonucleoproteins of the nuclear cap and of the Nissl bodies. They are morphologically and cytochemically distinct from inclusions of the nerve cell nucleus previously described in the literature as "nuclear rodlets".