Epinephrine-Induced Alterations in Connective Tissue of Aortic Wall in Rabbits.

Abstract

Alterations in rabbit aortas were brought about by intravenous administration of epinephrine. Microscopic examination revealed accumulation of metachromatic ground substance. The aortic content of hexosamine and water together with the uptake of S35-Sulfate was increased, whereas the amount of hydroxyproline was unaltered. The increase in the mucopolysaccharide/collagen ratio may indicate a reparative process.