INHIBITORY EFFECT OF CERTAIN AMINO ACIDS ON RENAL TUBULAR ABSORPTION OF PHOSPHATE
- 1 January 1967
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 45 (1), 103-114
- https://doi.org/10.1139/y67-011
Abstract
Infusion of certain neutral L-amino acids (alanine, glycine, valine, and tryptophan) into dogs resulted in an inhibition of the renal tubular reabsorption of phosphate and increased phosphate excretion. This was seen in both the parathyroidectomized animal and under conditions of exogenous parathormone infusion, indicating that the phosphaturia induced by amino acids is independent of parathyroid hormone action. This effect was stereospecific and did not occur with D-alanine; no effect was observed after infusion of the basic amino acids L-arginine and L-lysine.This publication has 12 references indexed in Scilit:
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