A VH gene is located within 95 Kb of the human immunoglobulin heavy chain constant region genes
- 1 November 1988
- journal article
- research article
- Published by Wiley in European Journal of Immunology
- Vol. 18 (11), 1843-1846
- https://doi.org/10.1002/eji.1830181130
Abstract
Using cosmids covering about 117 Kb upstream of the human immunoglobulin chain C, gene, we have identified a potentially functional VH gene, belonging to the VHVI subgroup. This VHVI gene is only about 95 Kb from the Cμ gene and is probably the first functional VH segment of the Igh locus. These results illustrate the proximity of the human VH, DH and JH segments involved in creation of the complete heavy chain genes.This publication has 22 references indexed in Scilit:
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