A genetic analysis of non-disjunction and mitotic recombination inNeurospora crassa

Abstract

SUMMARY: The frequency of the more common patterns of non-disjunction in Neurospora was studied. Detection of these asci was accomplished by the use of pantothenate requiring strains grown on reduced amounts of pantothenate, so that combinations of dark, pale, and aborted spores provided evidence of non-disjunction. The isolates from five non-disjunction asci were examined in detail and an apparently high frequency of mitotic recombination was detected for presumed disomic isolates. An hypothesis concerning a mechanism of non-disjunction is presented.