Distribution of 4-Iodoantipyrine After Intravenous Injection in the Rat
- 1 August 1962
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 11 (2), 252-256
- https://doi.org/10.1161/01.res.11.2.252
Abstract
The distribution of 4-iodoantipyrine does not parallel that of body water, as evidenced by its overaccumulation in some organs and underaccumulation in others. These disparities occur largely because I131 is lost from the iodoantipyrine molecule, is converted to iodide, and is distributed and excreted as such. Any similarity between the distribution volume of iodoantipyrine and total body water is, therefore, happenstance.Keywords
This publication has 5 references indexed in Scilit:
- THE EFFECT OF IODOPYRINE ON THE THYROID GLAND OF THE RATThe Lancet, 1959
- Measurement of Total Body Water in Sheep Using I131 Labeled 4-Iodo-AntipyrineExperimental Biology and Medicine, 1956
- Use of N-Acetyl 4-Aminoantipyrine (NAAP) in Measurement of Total Body WaterExperimental Biology and Medicine, 1951
- THE EXCRETION AND DISTRIBUTION OF I131FOLLOWING ADMINISTRATION OF PHYSIOLOGIC AMOUNTS OF LABELED IODIDE, DIIODOTYROSINE AND THYROXINE IN THE RAT1Endocrinology, 1951
- THE USE OF ANTIPYRINE IN THE MEASUREMENT OF TOTAL BODY WATER IN MANJournal of Biological Chemistry, 1949