Retinal Pigment Epithelial Cells in Culture Produce Retinal Vascular Mitogens
- 1 October 1988
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 106 (10), 1439-1443
- https://doi.org/10.1001/archopht.1988.01060140603031
Abstract
• Conditioned medium from human retinal pigment epithelial cells in culture significantly stimulated the proliferation of subcultured bovine retinal capillary endothelial cells, pericytes, and freshly isolated retinal microvessels. The vascular mitogenic activity enhanced that of retinal crude extract. No evidence emerged of an inhibitor of microvascular cellular proliferation produced by retinal pigment epithelial cells.This publication has 13 references indexed in Scilit:
- Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells.The Journal of cell biology, 1987
- A Retinal Pigment Epithelial Cell-Derived Growth Factor(s)Archives of Ophthalmology (1950), 1986
- Retina- and eye-derived endothelial cell growth factors: partial molecular characterization and identity with acidic and basic fibroblast growth factorsBiochemistry, 1985
- Retinal Pigment Epithelial Cells Release an Inhibitor of NeovascularizationArchives of Ophthalmology (1950), 1985
- Endothelial cell mitogens derived from retina and hypothalamus: biochemical and biological similarities.The Journal of cell biology, 1984
- Human Endothelial Cells: Use of Heparin in Cloning and Long-Term Serial CultivationScience, 1983
- Culture of retinal capillary cells using selective growth mediaMicrovascular Research, 1983
- The Endothelial Cells of Large and Small Blood VesselsDiabetes, 1981
- ENDOTHELIAL FENESTRAE IN PROLIFERATIVE DIABETIC-RETINOPATHY1980
- Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment processProceedings of the National Academy of Sciences, 1977