Alterations in Serum Proteins and 19S Antibody Production during the Course of Induced Malarial Infections in Man

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Abstract
Summary Increases in β 2M macroglobulins have been detected by means of immunoelectrophoresis during the course of induced malarial infections in man. The increase in this serum globulin coincides closely with the appearance of antibodies to malaria as detected by fluorescent antibody studies. Evidence is presented that 19S β 2M macroglobulin antibodies as well as 7S gamma globulin antibodies are formed during the course of primary malarial infections in human volunteers.