σ-Chelation-directed C–H functionalizations using Pd(ii) and Cu(ii) catalysts: regioselectivity, stereoselectivity and catalytic turnover

Abstract

Recent progress in σ-chelation directed C–H functionalization from the authors' group is described to illustrate the challenges and opportunities in the development of synthetically-useful catalytic reactions involving C–H activation as the key step. Emphasis is placed on strategies for developing catalysis under mild conditions and controlling regio- and stereoselectivity.