Change with Age of Anisotropic Properties of Collagen Bundles
- 1 January 1979
- journal article
- research article
- Published by S. Karger AG in Gerontology
- Vol. 25 (1), 2-8
- https://doi.org/10.1159/000212314
Abstract
Form birefringence curves and linear dichroic properties of aging rat tendons are different from those of adult controls. The steepness of the form birefringence curves and the increased retardations found in aging tendons are ascribed to an increase in collagen aggregation accompanied by loss of tissue water. Based on increase of retardations due to intrinsic birefringence, a rise in crystallinity levels is suggested for the collagen bundles of aging tendons. The inversion of the dichroism signs and the change in the d∣∣ (collagen fibers oriented parallel) and d1 (collagen fibers oriented perpendicular) spectral absorption profiles, mainly at the absorption peaks for sections stained with toluidine blue solutions at pH 4.0 and 5.0, indicate modifications at the acid glycosaminoglycan molecular orientation level with advancing age.Keywords
This publication has 6 references indexed in Scilit:
- Changes in cells, matrix and water of calcifying turkey leg tendonsJournal of Anatomy, 1967
- THERMAL SHRINKAGE PROCESS OF COLLAGEN FIBRES AS REVEALED BY POLARIZATION OPTICAL ANALYSIS OF TOPOOPTICAL STAINING REACTIONS1967
- Age Variations of Nominal Tensile Strength of Wistar Rat SkinsGerontology, 1964
- Aging of the Collagen FiberPublished by Elsevier ,1964
- Connective Tissue III. Collagen and Hexosamine Content of Tissues of Rats of Different Ages.Experimental Biology and Medicine, 1960
- Studies On The Effect Of Heat And Age An Decreasing Ability Of Human Collagen To Swell In AcidJournal of Gerontology, 1959